Wegovy come in 5 different doses, the beginning dose is 0.25 mg once a week for the first 4 weeks. This will give your body a chance to get used to the medicine. At Week 5, you will increase the dose to 0.5 mg once a week, followed by 1.0mg. Then if needed, increase the dose to 1.7mg and then 2.4mg. Once you have reached 2.4mg you remain on that for the duration of your treatment.